Does Testosterone Therapy Help People Lose Weight? Answers To Your Burning Hormone Questions
- FreshRx
- Nov 6, 2024
- 4 min read
Updated: Nov 6, 2024

Lately, the health and wellness medical industry is seeing growing interest in testosterone therapy, especially among men who are experiencing symptoms of low testosterone (like fatigue, lack of motivation, brain fog, reduced physical stamina, and more). One (understandably) common inquiry that we get from our patients at FreshRx is whether testosterone therapy (TRT) can aid in weight loss.
Given testosterone's impact on muscle mass, energy levels, and metabolism, it is certainly reasonable to assume that body weight and testosterone levels may be linked. While it is not the only factor, testosterone is an important body chemistry factor that impacts overall health and quality of life.
What exactly is Testosterone Therapy?
Let's start at the beginning. Testosterone therapy (TRT) typically involves the administration of testosterone through injections, patches, or gels to supplement natural levels in individuals diagnosed with low testosterone. TRT is prescribed with the intention of improving symptoms related to low testosterone like fatigue, low libido, and even mental health issues. Weight loss is definitely not the primary purpose of TRT. However, TRT patients are very often able to use the benefits of TRT to lose weight if they need to and improve overall health and fitness. TRT patients love testosterone therapy for the reinvigorated energy and motivation they experience, which almost always leads to better health and fitness.

How Testosterone Affects Body Composition
Testosterone also has some more direct affects on body composition. Testosterone influences muscle mass, bone density, and fat distribution—especially in men. Low testosterone is often associated with an increase in body fat, particularly visceral fat (fat around the organs), which can contribute to health issues like diabetes and heart disease. Restoring normal testosterone levels through TRT can increase lean muscle mass, boost metabolism, and improve energy, potentially leading to fat loss.
Testosterone and Metabolism
Testosterone even influences metabolism! People with healthy testosterone levels often have higher resting metabolic rates, which allows them to burn more calories even at rest. By increasing muscle mass, which burns more calories than fat, testosterone can naturally increase the body's energy demands. This can make weight loss easier or more achievable when combined with a balanced diet and exercise. Sounds like a magic bullet, right?! Well, our patients will tell you that it's close, BUT, it is important to be aware that testosterone alone won’t result in major weight loss without lifestyle changes.

Clinical Evidence: Studies on Testosterone Therapy and Weight Loss
Responsible providers and patients love to know what the research says. Luckily, there are research findings on testosterone therapy and its potential to aid in weight loss. For example, studies show that TRT may reduce body fat while increasing muscle mass, particularly in men with low testosterone. Below is a summary of some significant research findings that support testosterone's role in weight management:
Men in one study experience a reduction in visceral fat and overall body fat on TRT (compared to those not on TRT).
TRT can improve insulin sensitivity, which may help people manage weight better by stabilizing blood sugar levels.
TRT enhances energy levels, making physical activity more feasible, which indirectly supports weight loss efforts.
Testosterone Therapy vs. Lifestyle Changes
Listen, nothing beats living a healthy lifestyle. It sounds so easy, but if it were really that easy, everyone would do it, and no one would need ANY medications at all! Lucky for us, we are fortunate enough to be living in an era of truly magnificent medical innovations. The medicines that we have access to are not necessarily "magic bullets," but they are the closest things to magic bullets that this world has ever seen.
All of this is to say that testosterone therapy is not a replacement for traditional weight loss methods. A healthy diet, regular exercise, and adequate sleep remain essential. While TRT may offer a "boost," lifestyle changes will always play a primary role in achieving sustainable weight loss. Explain that, in most cases, TRT is more effective when combined with lifestyle modifications, as the energy and muscle improvements from testosterone can enhance workout performance and improve adherence to a healthy diet.
Considerations and Cautions
While testosterone therapy is an amazing treatment for many men, TRT isn’t necessarily suitable for everyone. Candidates for TRT should be medically evaluated by a licensed prescriber to ensure that their testosterone levels are low enough to replace! At FreshRx, your labs are not drawn once, not twice, but several times to ensure that patients are safe candidates to start treatment and to remain on treatment throughout their TRT journey.

Periodic follow-up appointments are important to us at FreshRx not only to monitor labs, but also for potential side effects. Some of our other blog posts in "Fresh Perspectives" discuss potential risks of TRT in detail. The potential risk for blood clots can be avoided by testing labs periodically to monitor each patient's hematocrit. While prostate issues on TRT are becoming less of a concern as more research is completed, any potential markers of disease can be identified in bloodwork with plenty of time to treat them.
Some people out there still undergo TRT in a very casual setting, without any monitoring by medical professionals. Hopefully after reading some of our "Fresh Perspective" blog posts, you agree on the importance of medically managed TRT guided by a licensed prescriber to ensure safe and effective results! With the help of our qualified Nurse Practitioner, you will receive the BEST care.
To summarize, while testosterone therapy can support weight loss efforts indirectly by increasing muscle mass, energy levels, and metabolic rate, it isn’t a guaranteed or standalone solution for weight loss. Instead, TRT can provide great help to address weight challenges more effectively (when combined with a healthy lifestyle, as always).
If you are interested in exploring TRT, reach out to FreshRx for a free consult! We will discuss with you symptoms, potential benefits, any risks involved, and we will help you decide what kind of treatment is right for you. This way, you can make informed decisions that best support your health and your individual wellness goals.

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